Prof. Satoru Miyano
Tokyo Medical and Dental University, Japan
Satoru Miyano, PhD, is the Founding Director of M&D Data Science Center, Tokyo Medical and Dental University in April 2020 after finishing his mission of Director of Human Genome Center, the Institute of Medical Science, the University of Tokyo. 2018 SIP AI Hospital Project sub Program Director. He received the B.S. (1977), M.S. (1979) and PhD (1984), all in Mathematics from Kyushu University, Japan. He is 2013 Fellow of the International Society for Computational Biology. He received 2016 Uehara Award for cancer genomics and 2020 Healthy Society Award on pioneer division.
Prof. Hongmin Cai
South China University of Technology, China
Dr. Hongmin Cai is a professor and doctoral supervisor at the School of Computer Science and Engineering, South China University of Technology. Prof. Cai is a guest professor at Kyoto University, a member of the Bioinformatics and Artificial Life Committee of CAAI, a member of the Bioinformatics Committee and Standing Committee of CCF, and a PC Member of many international conferences such as ISBI, ISBRA, ICIC, BIBM and GIW. Professor Cai is also the Chairman of ICDKE 2012, ICBBB2021, ICBBB 2022, Vice Chairman of Guangdong Translational Medicine Ophthalmology Branch, Vice Chairman of Guangdong Precision Medicine Application Society - Digital Intelligence Branch, Vice Chairman of Guangdong Biomedical Engineering Society Intelligent Medical Imaging Branch. Professor Cai has been involved in the research works on biomedical image and bioinformatics. He has accumulated rich research experience in the fields of medical image analysis and understanding, bioinformatics, multi-source data fusion, pattern recognition and data mining. In esteemed journals such as IEEE T-PAMI, IEEE T-Cybern, IEEE T-Image Proce., IEEE T-Medical Imaging, NeuroImage, Bioinformatics, Briefings in Bio., more than 100 SCI/EI papers have been published, including 80 SCI/EI papers regarding Professor Cai as the corresponding author or the first author. The total IF of the papers in recent 5 years exceeds 200.
Speech Title: "Recent Advances Integration Analysis for Biomedical Data from Multiple Sources"
Abstract: With the popularization of new generation sequencing technology and the rapid development of single cell sequencing technology, multi-omics data at different scales are derived. With the rapid development of various new imaging technologies, multimodal image data under different imaging conditions are derived. Such multi-source data has problems such as small sample size, high dimension, multi-mode, cross-scale and multi-attribute missing, etc. It is of great scientific significance to integrate and analyze such multi-source heterogeneous data, which can provide computing tools for life computation and medical assisted diagnosis. Our lab focus on the integration theory on multi-source heterogeneous data. We established a tensor spectral clustering theory for small sample learning, to realize the effective fusion of multi-source information. We carried out on analyzing the data from micro multi-omics and macro medical imaging. This report will report the recent advances of our laboratory in the above aspects.
Prof. Ying Xu, H-Index: 66
University of Georgia, USA
Ying Xu has been the "Regents and Georgia Research Alliance Eminent Scholar" Chair of bioinformatics and computational biology and Professor in Biochemistry and Molecular Biology Department since 2003 and was the Founding Director of the Institute of Bioinformatics, the University of Georgia (UGA). He received his Ph.D. degree in theoretical computer science from the University of Colorado at Boulder in 1991. He started his bioinformatics career in 1993 when he joined Oak Ridge National Lab, where he worked for ten and half years. In 2003, he was recruited to the UGA to build the Institute of Bioinformatics. His current research interests are in cancer bioinformatics and systems biology, particularly in cancer metabolism. He has over 300 publications, including five books, with total citations more than 16,000 and H-Index = 66; and has given over 250 invited/contributed talks at conferences, research organizations and universities.
Prof. Yoshio Kodera
Kitasato University, Japan
Speech Title: Peptidomics Based on a High-Yield Peptide Extraction Method
Abstract: With the development of mass spectrometry technology, it is now possible to quantitatively analyze nearly 10,000 different proteins in a two-hour analysis of enzymatic digests of proteins from cell and tissue samples. However, in blood samples, the existence of high-abundance proteins and the large dynamic range of protein concentration make any analysis of low-abundance proteins challenging. In particular, detailed analysis of low molecular weight proteins/peptides is extremely difficult due to the carrier protein binding. We developed ultra-high yield peptide extraction method. The method, which we named “differential solubilization (DS)”, efficiently depleted plasma highly abundant proteins with minimal loss of peptides that were both unbound and bound to carrier proteins such as albumin. Based on DS method, we successfully identified more than 10,000 peptides from 0.2 mL plasma including well-known bioactive peptides and discovered four novel bioactive peptides. Furthermore, the modified DS method enabled highly efficient and reproducible peptide extraction from frozen sub-milligram sections of a single mouse hypothalamus and successfully detected more than 1,500 peptides including diverse authentic bioactive peptides.
Prof. Yoshinobu Kimura
Okayama University, Japan
Dr. Yoshinobu KIMURA is a professor at the Graduate School of Environmental and Life Science and a Dean of Faculty of Agriculture, Okayama University. He received his Ph.D. from Kyushu University (Department of Agricultural Chemistry) in 1987. He started his professional career in 1987 as assistant professor and was promoted to an associate professor (1992), professor (2003) at Okayama University. He was a visiting associate at NHLBI (Dr. Thressa C. Stadtman), National Institutes of Health (NIH, USA) in 1992-1993, a visiting researcher at Friedrich-Miescher Institutes (Basel, Switzerland) in 1997 and at the Glycobiology Institute, Oxford University (UK) in 2002. He received the Japanese Agricultural Chemical Society Award for Young Scientists (1998) and the Award for Excellence to Authors Publishing in Bioscience, Biotechnology, and Biochemistry (2005). His recent research interests include functional glycomics of free N-glycans involved in the protein-folding system, the plant development or growth, and the immunological response.
Speech Title: "Generating Mechanism and Biological Functions of Free N-glycans Ubiquitously Occurring in Plants"